Update – African Cattle Genomics Exchange https://cattle-genomix.net Fri, 25 May 2018 09:27:47 +0000 en-US hourly 1 https://wordpress.org/?v=4.9.7 Support for Genomics Reference Resource for African Cattle https://cattle-genomix.net/summary-3/ https://cattle-genomix.net/summary-3/#respond Mon, 22 Aug 2016 13:49:51 +0000 http://cattle-genomix.net/?p=422 Summary of discussion to-date on the topic: Do you consider building a genomics reference resource for African cattle to be a worthwhile investment – why or why not?

 

In favour?

The majority of people who commented on this question were in favour of establishing the resource, with some raising pertinent issues related to resource utility and design (see below). These participants were challenged to expand on how they thought the resource would be useful (responses are still coming in)

A minority of people did not feel the resource was a current priority – in relation to AnGR use they felt emphasis would be better placed on establishing basic, functional genetic improvement programs (linked to delivery systems), as well as capacity building on animal breeding / genomics in general.

 

Key points raised in relation to increasing the utility of the resource or on resource design:

  • Design must lead to exciting and useful results generated from the early investment, to provide incentives for future investments
  • Animals should be strategically sampled e.g. influential sires
  • Link to phenomic characterization of animals will increase the utility of the resource

 

 

]]>
https://cattle-genomix.net/summary-3/feed/ 0
Future applications of genomics in African livestock systems https://cattle-genomix.net/summary-2/ https://cattle-genomix.net/summary-2/#comments Mon, 22 Aug 2016 11:46:02 +0000 http://cattle-genomix.net/?p=417 What genetic or genomic applications have the most potential to positively impact on the rural poor in Africa – in the near future and longer term?

 

Main themes discussed on this topic to-date are:

The need for a holistic outlook on improving the performance of African livestock was stressed by many. Points raised here included:  the need for  supportive policy; the need for strong livestock product markets, as well as ability of livestock keepers to access these markers;  intervention package to address the various livestock production constraints (including on feed, health etc.); and means for farmers to access new technologies, such as public-private partnerships, amongst others.  In general, these issues are a subset of those commonly recognized by those working in the African livestock sectors.

 

Of the potential applications of genomics / genetics in African livestock systems, the only one discussed in any detail was genomic selection.  Here discussion centered around

1)Whether / how African livestock systems could capitalize on the opportunity of genomic selection, given current  system constraints.  Some example comments are:

  • “Genomic tools are not a silver bullet. …(for)  any livestock improvement effort to bear fruit requires that the basics need to be in place i.e. the conventional livestock recording systems which are not existent in most developing countries”
  • “Application of genomic tools is constrained by inefficient breeding programmes and policies in our African countries”
  • “Current genomic tools offer a ray of hope but the basic infrastructure for conventional animal performance recording are still necessary”

2) How reference populations could be created – with the suggestion of using data from government institutions linked to data from (the often few) producers who record. The latter to assist in dealing with issues related to GxE

3) An example was given of a project on Kenyan dairy cattle (mainly cross-bred) where genomic prediction was undertaken (using GBLUP and Bayes C) based on about 1000 animals with phenotypes (milk records) and genotypes, with resultant accuracies of 0.3 to 0.4.

 

The need for recording schemes – with appropriate incentives for farmer engagement – was also a common theme. The only incentive explicitly discussed, however, was the use of records to help improve farm management decisions (seen as being more immediate than that related to generation of genetically improved animals). There was general agreement that farmers needed capacity building in recording, and that timely feedback (on the records) was important.

 

]]>
https://cattle-genomix.net/summary-2/feed/ 2
Current use of genomics / genetics in African livestock systems https://cattle-genomix.net/summary-1/ https://cattle-genomix.net/summary-1/#comments Wed, 17 Aug 2016 14:48:58 +0000 http://cattle-genomix.net/?p=371 Below is a summary of contributions to date on the topic “What (real) examples of the application of genomic or genetic information to African livestock production systems (regardless of species) do we have to-date, and what was successful or not successful about these, and why”

Updated 22nd August, 2016

Application Country Species / traits Intended use Actual use Contributor
Genetic diversity/population structure Nigeria Goats,

some sheep, chicken,

few cattle

Abdulmojeed Yakubu
Cameroon Cattle To inform breeding and conservation decisions Ngono Ema
Pathogen detection / disease diagnostics Nigeria Swine, cattle, poultry Animal health applications, championed by

National Veterinary Institute

Oladeji Bamidele

 

Abdulmojeed Yakubu

Breed composition of admixed populations Senegal Cattle Comparison of productivity and household profit for keeping different breed-types – to create an evidence base for a genetic improvement strategy Karen Marshall
Rwanda Cattle  Identification of bull calves as a source of germplasm and breeding lines, in relation to a ‘One Cow per Family’ program Mizeck Chagunda
Kenya Cattle-dairy Feeding into test of genomic prediction ability (see below) Raphael Mrode
Breeding program using genomic predictions Kenya Cattle – dairy Test of genomic prediction ability  (using GBLUP & Bayes C; 1000 genotyped and phenotyped crossbred animals)

 

Raphael Mrode
Identification of underlying genes / gene-networks Nigeria Cattle (local) – heat tolerance & productivity Genetically improved animals Oladeji Bamidele

 

See what others have contributed and contribute your insights and suggestions

]]>
https://cattle-genomix.net/summary-1/feed/ 2
Welcome to the Cattle Genomics in Africa web forum https://cattle-genomix.net/welcome-to-the-cattle-genomics-in-africa-web-forum/ https://cattle-genomix.net/welcome-to-the-cattle-genomics-in-africa-web-forum/#comments Tue, 16 Aug 2016 07:06:14 +0000 http://cattle-genomix.net/?p=319 Dear colleagues,

Today we are launching our discussion. During the coming two weeks we will focus on:

  • Current and future applications of genomics to cattle in Africa – in particular, which applications are likely to make a difference to poor livestock keepers and animal source food consumers, and what capacities and resources are required to achieve this.
  • The potential to create a genomic reference resource on African cattle – a publically-available set of sequence information on cattle breeds in Africa,  and critically which breeds to prioritize for this.

 

You are already a member of the community. To join the discussion please log in at http://cattle-genomix.net

We look forward to your participation.

Karen Marshall

The International Livestock Research Institute & the Centre for Tropical Livestock Genetics and Health.

 

]]>
https://cattle-genomix.net/welcome-to-the-cattle-genomics-in-africa-web-forum/feed/ 6
Building a genomic reference resource on African cattle https://cattle-genomix.net/topic-2/ https://cattle-genomix.net/topic-2/#comments Fri, 27 May 2016 08:38:32 +0000 http://cattle-genomix.net/?page_id=51 Here we will discuss the need and potential for a Genomics Reference Resource for African Cattle – which is a collated and publicly accessible set of sequence information on African cattle breeds. The sequence information would be contributed by African countries and potentially other partners to the initiative, with the intent that such information will help facilitate the application of genomics to benefit the African cattle sectors.

For more on this potential initiative, please see this post on a ‘Genomics reference resource for Africa

Genomics_Building1

We are currently discussing two topics in relation to this (and more topics will follow as the forum progresses):

(1)  Do you consider building a genomics reference resource for African cattle to be a worthwhile investment – why or why not?

Click here for a summary of contributions on this topic to-date

(2) What are the strategic research questions we can answer, or applications we can facilitate, with such a resource

Please submit your contributions on these by posting below. Use the comment box (scroll down) to add a new comment, or reply to existing comments using the reply button.

 

]]>
https://cattle-genomix.net/topic-2/feed/ 59
Using genomic information on cattle in Africa https://cattle-genomix.net/topic-1/ https://cattle-genomix.net/topic-1/#comments Fri, 27 May 2016 07:39:18 +0000 http://cattle-genomix.net/?page_id=49 Here we are discussing the applications of genomic (or genetic) information on cattle in Africa, both in the near future (next 5 years) and longer term.

Some potential applications are given below (see also this post on the potential role of genomics for African cattle)

Genomics_Use2

 

We are currently discussing two topics in relation to this (and more topics will follow as the forum progresses):

(1)  What (real) examples of the application of genomic or genetic information to African livestock production systems (regardless of species) do we have to-date, and what was successful or not successful about these, and why

Click here for a summary of contributions on this topic to-date

(2) Which genomic or genetic applications have the most potential to positively impact on the rural poor in Africa – in the near future and the longer term.

Click here for a summary of contributions on this topic to-date

(3) Is phenomics – the ability to measure livestock performance – a bigger challenge than genomics in African livestock systems and, if so, how can we increase phenomic capabilities

Please submit your contributions on these by posting below. Use the comment box (scroll down) to add a new comment, or reply to existing comments using the reply button.

 

Genomics_Use1

]]>
https://cattle-genomix.net/topic-1/feed/ 121